Metformin in renal failure--weigh the evidence
نویسندگان
چکیده
منابع مشابه
Metformin induced acute pancreatitis precipitated by renal failure.
Metformin is a biguanide commonly used in type 2 diabetes and considered to be a safe drug with minimal side effects. Approximately 2% of cases of acute pancreatitis may be caused by drugs, but it is not a known complication of metformin therapy. To date only one case of pancreatitis has been reported in association with metformin, but that was secondary to metformin poisoning (overdose). This ...
متن کاملMetformin lactic acidosis, acute renal failure and rofecoxib.
A patient with acute renal failure associated with lactic acidosis as a result of concurrent treatment with metformin is described. Rofecoxib may have been a precipitating factor. The risk of renal failure with the use of traditional NSAIDs is well known. However, what is less well appreciated is the role that the COX 2 inhibitors may play in the development of renal failure which, when it occu...
متن کاملMetformin in heart failure.
W e recently learned of an important change in the prescribing information for metformin, previously contraindicated in patients with type 2 diabetes accompanied by heart failure (HF) requiring pharmacological therapy. The contraindication was introduced to the label soon after the drug’s U.S. release, when case reports emerged of HF patients taking metformin who developed lactic acidosis. It w...
متن کاملSecondary Failure of Metformin Monotherapy Secondary Failure of Metformin Monotherapy in Clinical Practice Running Title: Secondary Failure of Metformin Monotherapy
This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...
متن کاملThe safety of metformin in heart failure.
OBJECTIVE To examine the evidence regarding the safety of metformin in heart failure. DATA SOURCES Searches in MEDLINE and International Pharmaceutical Abstracts were performed (1966-February 2007). Search terms included metformin, heart failure, lactic acidosis, clinical trials, and insulin resistance. STUDY SELECTION AND DATA EXTRACTION Published studies and case reports that evaluated th...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2009
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfp197